Targeting QPCT Activity: A New Frontier in Disease Intervention
Proteins usually help the body stay healthy, but sometimes they change into harmful versions. The problem isn’t the proteins themselves but how enzymes modify them after production. One such enzyme is glutaminyl-peptide cyclotransferase, or QPCT for short. This enzyme alters the composition of amyloid-beta proteins by creating pyroglutamate-modified amyloid-beta (pGlu-Aβ). The modified version can become […]
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